Paragonimus IgG ELISA Kit
The Paragonimus IgG ELISA Kit is a semi-quantitative enzyme-linked immunosorbent assay (ELISA) used for detecting IgG antibodies specific to Paragonimus species in human serum or plasma samples. Paragonimiasis is a foodborne zoonotic disease caused by lung flukes (flatworms) of the genus Paragonimus. Humans become infected by consuming raw or undercooked freshwater crabs or crayfish harboring infectious larvae. Severe cases may involve migration of the parasite to the central nervous system, leading to meningitis and other complications.
The disease is prevalent in parts of Asia (China, Japan, Korea, Vietnam), Africa, and Central and South America, particularly in regions where consumption of freshwater crabs or crayfish is common. Once ingested, the larvae migrate to the lungs, maturing into adult flukes within 6-10 weeks. Early symptoms include diarrhea and abdominal pain, followed by chest pain, fever, fatigue, and coughing. The cough may progress to produce rusty-colored or blood-tinged sputum, mimicking symptoms of tuberculosis.
This kit uses microplates coated with Paragonimus antigens. During the assay, IgG antibodies in patient serum bind to the antigens. Enzyme conjugate and chromogen (TMB) are subsequently added, producing a color change that indicates positive results. The assay provides clear and accurate results, readable visually or with an ELISA reader.
Paragonimus IgG ELISA Kit
