Strongyloides IgG ELISA Kit
The Strongyloides IgG ELISA Kit is a qualitative enzyme-linked immunosorbent assay (ELISA) designed for detecting IgG antibodies to Strongyloides stercoralis in human serum or plasma. Strongyloides stercoralis is an intestinal nematode with global distribution, particularly prevalent in tropical and subtropical regions.
Infected individuals typically experience mild diarrhea and intestinal symptoms. However, in severe cases, the parasite can migrate outside the intestine, leading to pulmonary infections, septic shock, or meningitis. Immunocompromised patients, such as those undergoing immunosuppressive therapy, are at a higher risk of severe and life-threatening complications, making early diagnosis crucial.
The assay uses L3 stage larval antigens coated on microplates. During testing, IgG antibodies in the sample bind to the antigens, followed by enzyme conjugate and chromogen (TMB) addition, producing a visible color change. Results can be observed visually or measured using an ELISA reader, providing a rapid and accurate diagnosis of Strongyloides infections.