Spirometra IgM ELISA Kit
The Spirometra IgM ELISA Kit is a qualitative enzyme-linked immunosorbent assay (ELISA) designed to detect IgM antibodies to Spirometra species in human serum samples. It is intended for early diagnosis of sparganosis and must be used by trained medical technologists.
Spirometra is a parasitic worm that completes its lifecycle in dogs and cats as definitive hosts. Humans acquire sparganosis as paratenic or secondary intermediate hosts through drinking water containing infected copepods or consuming undercooked intermediate host meat (e.g., snake or frog). Once infected, larvae can migrate to various locations, including subcutaneous tissue, pleural cavity, lungs, urinary tract, and the central nervous system, where they can survive for up to 20 years.
Clinical manifestations of sparganosis depend on the parasite's location. While subcutaneous infections are usually painless, migration to the central nervous system can result in neurological symptoms such as headaches, seizures, weakness, and numbness. Inner ear involvement may lead to vertigo or hearing loss. This kit uses recombinant Spirometra cysteine protease antigen-coated microplates to detect IgM antibodies, providing reliable diagnostic results through visual or ELISA reader interpretation.